Publications

CHAARM publications and other dissemination activities 2010-2011

Publications:

  • Venkatraj M. , Ariën KK , Heeres J. , Dirié B., Joossens J. , Van Goethem S. , Van der Veken P., Michiels J. , Vande Velde C. M.L. , Vanham G. , Lewi P.J. , Augustyns K. (2011), Novel diarylpyridinones, diarylpyridazinones and diarylphthalazinones as potential HIV-1 nonnucleoside reverse transcriptase inhibitors (NNRTIs), Bioorganic & Medicinal Chemistry, 19 5924–5934.

http://www.sciencedirect.com/science/article/pii/S0968089611006948

  • Ariën KK, Gali Y, Vanham G. (2011). The “gatekeeper” hypothesis challenged in a human cervico-vaginal tissue model for HIV-1 transmission. Mucosal Immunology Mucosal Immunology, 4(1):121-122

http://www.nature.com/mi/journal/v4/n1/full/mi201045a.html

  • Ariën KK, Vanham G, Gali Y. (2010). A dual chamber model of the female genital tract in screening for epithelial toxicity. Current Protocols in Cell Biology. (In PubMed press)

http://www.ncbi.nlm.nih.gov/pubmed/20138087

  • Jespers V, Harandi AM, Hinkula J et al. (2010). Assessment of mucosal immunity to HIV-1. Expert Rev Vaccines. Vol.9:381-394.

http://www.expert-reviews.com/doi/abs/10.1586/erv.10.21

  • Jespers V, Francis SC, van de Wijgert J, Crucitti T. (2010). Methodological issues in sampling the local immune system of the female genital tract in the context of HIV prevention trials. Am J Rep Imm. Vol. 65, Issue 3:368-376

http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0897.2010.00938.x/abstract;jsessionid=9574033E4E58D81874BA3E718DD35B3F.d03t01
 

  • Selhorst P, Vazquez AC, Terrazas-Aranda K, Michiels J, Vereecken K, Heyndrickx L, Weber J, Quiñones-Mateu ME, Ariën KK, Vanham G. (2010). Human Immunodeficiency Virus Type 1 (cross-) resistance to non-nucleoside reverse transcriptase inhibitors currently under development as microbicides. Antimicrobial Agents and Chemotherapy (in revision)
  • Ariën KK, Vanham G. (2010). First real success for anti-HIV gel - a new start for HIV microbicides? (Editorial). Future Microbiology 5:1621-1623

http://www.futuremedicine.com/doi/full/10.2217/fmb.10.129
 

  • Gali Y, Delezay O, Brouwers J, Addad N, Augustijns P, Bourlet T, Hamzeh-Cognasse H, Ariën KK, Pozzetto B, Vanham G. (2010). In vitro evaluation of viability, integrity and inflammation in genital epithelia upon exposure to pharmaceutical excipients and candidate microbicides. Antimicrobial Agents and Chemotherapy. (in PubMed Press), 54(12): 5105-5114

http://www.ncbi.nlm.nih.gov/pubmed/20921308
 

  • Gali Y, Ariën KK, Praet M, Van den Bergh R, Temmerman M, Delezay O, Vanham G. (2010). Development of an in vitro dual chamber model of the female genital tract as a sceening tool for epithelial toxicity. Journal of Virological Methods, 165(2): 186-197

http://www.ncbi.nlm.nih.gov/pubmed/20138087
 

  • Britta Wahren, Priscilla Biswas, Marie Borggren, Adam Coleman, Kelly Da Costa, Winni De Haes, Tessa Dieltjens, Stefania Dispinseri, Katrijn Grupping, David Hallengärd, Julia Hornig, Katja Klein, Lara Mainetti, Paolo Palma, Marc Reudelsterz, Janna Seifried, Philippe Selhorst, Annette Sköld, Hannes Uchtenhagen, Marit J van Gils, Caroline Weber, Robin Shattock, and Gabriella Scarlatti. (2010). Rational design of HIV vaccine and microbicides: report of the EUROPRISE annual conference. J Transl Med.; 8: 72.  [Electronic version, 2010, July 26]

http://www.translational-medicine.com/content/8/1/72
 

  • Coiras M, López-Huertas MR, Sánchez del Cojo M, Mateos E, Alcamí J. (2010). Dual Role of Host Cell Factors in HIV-1 Replication:Restriction and Enhancement of the Viral Cycle. AIDS Rev. 2010 Apr-Jun;12(2):103-12. Review. PMID: 20571604

http://www.aidsreviews.com/resumen.asp?id=1089&indice=2010122
 

  • Bedoya LM, Abad MJ, Calonge E, Saavedra LA, Gutiérrez CM, Kouznetsov VV, Alcami J, Bermejo P. (2010). Quinoline-based compounds as modulators of HIV transcription through NF-B and Sp1 inhibition. Antiviral Res. 2010, Sept.; 87(3):338-44. PMID: 20600334

http://www.ncbi.nlm.nih.gov/pubmed/20600334
 

  • Poveda E, Alcamí J, Paredes R, Córdoba J, Gutiérrez F, Llibre JM, Delgado R, Pulido F, Iribarren JA, García-Deltoro M, Hernández-Quero J, Moreno S, García F. (2010). Genotypic Determination of HIV Tropism - Clinical and Methodological Recommendations to Guide the Therapeutic Use of CCR5 Antagonists. AIDS Rev., 2010 Jul-Sep;12(3):135-48. Review PMID: 20842202.

http://www.aidsreviews.com/resumen.asp?id=1097&indice=2010123
 

  • González N, Alvarez A, Alcamí J. (2010). Broadly Neutralizing Antibodies and their Significance for HIV-1 Vaccines. Curr HIV Res. 2010 Nov 5.; PMID: 21054253

http://www.ncbi.nlm.nih.gov/pubmed/21054253

  • Coiras M, López-Huertas MR, Sánchez del Cojo M, Mateos E, Alcamí J. (2010). HIV Latency – Treatment of Viral Infection and Prospects for the Eradication of Latent Reservoirs. European Infectious Disease, 2010 March 3;4(2):10-6.

http://www.discoverymedicine.com/Mayte-Coiras/2010/03/03/hiv-1-latency-and-eradication-of-long-term-viral-reservoirs/
 


Events abstracts:

  • Jespers V, Poradosú S, Vanham G, Goovaerts O, Michiels J, Ariën K. (2010)

Optimising endocervical mucosal cell sampling for the study of HIV mucosal target cells in microbicide and mucosal vaccine research.
International Microbicides Conference (M2010), 22-25 May 2010, Pittsburgh, USA (oral poster presentation)

  • Selhorst P, Terrazas-Aranda K, Michiels J, Heyndrickx L, Vazquez A, Quinones-Mateu M, Ariën K, Vanham G. (2010)

Assessing HIV-1 Cross-Resistance in vitro against RTI-based Microbicides Currently Under Development.
International Microbicides Conference (M2010), 22-25 May 2010, Pittsburgh, USA (oral poster presentation)

  • Gali Y, Delezay O, Brouwers J, Bourlet T, Pozzetto B, Hamzeh-Cognasse H, Augustijns P, Ariën K, Vanham G. (2010)

In vitro evaluation of the safety profile of pharmaceutical excipients for the use in microbicide formulations.
International Microbicides Conference (M2010), 22-25 May 2010, Pittsburgh, USA (oral poster presentation)

  • Selhorst P, Vazquez AC, Terrazas-Aranda K,  Michiels J, Heyndrickx L, Ariën K, Quiñones-Mateu ME, Vanham G. (2010)

In vitro HIV-1 Cross-Resistance against RTI-based Microbicides
International HIV & Hepatitis Virus Drug Resistance Workshop and Curative Strategies, 8-12 June 2010, Dubrovnik, Croatia

  • Grupping K, Heyndrickx L, Ariën K, Martin G, Martin L, Vanham G. (2010)

Resistance Induction to the HIV-1 CD4 Binding Site Inhibitor M48-U1.
International HIV & Hepatitis Virus Drug Resistance Workshop and Curative Strategies, 8-12 June 2010, Dubrovnik, Croatia
 

  • Selhorst P, Terrazas-Aranda K, Michiels J, Heyndrickx L, Vazquez A, Quinones-Mateu M, Ariën K, Vanham G. (2010)

In vitro activity of candidate microbicides against cell-associated HIV.
5th International Workshop on HIV Transmission, 15 - 16 July 2010, Vienna, Austria (oral presentation)

  • Selhorst P, Grupping K, Michiels J, Ariën K, Vanham G. (2011)

Inhibition of cell-associated virus by candidate microbicides.
Keystone Symposium “Protection from HIV: Targeted Intervention Strategies”, 20-25 March 2011, Whistler, BC, Canada.